Review paper on fertility preservation in children and prepubertal adolescents with gynaecological cancer

Eur J Surg Oncol. 2024 Nov 20:109483. doi: 10.1016/j.ejso.2024.109483. Online ahead of print.

Abstract

Gynaecological cancer incidence in children and prepubertal girls is low but the risk of losing fertility potential is high due to the oncological treatments' toxicity. Consequently, fertility preservation is a top concern for survivors. This narrative review aims to summarize the best way of approaching each tumor treatment during prepubertal age with the goal of preserving fertility, and to discuss the latest methods used for fertility preservation for each gynaecological cancer. These procedures do not lack risks or uncertainities and offer a broad area of research.