Engineering biology approaches to modulate bacterial biofilms

Trends Biotechnol. 2024 Dec 5:S0167-7799(24)00314-7. doi: 10.1016/j.tibtech.2024.11.002. Online ahead of print.

Abstract

Building on a productive two decades of advancements in synthetic biology, engineering biology now promises to enable the implementation and scale-up of novel biological systems tailored to tackle urgent global challenges. Here we explore the latest engineering biology approaches for the control and modification of bacterial biofilms with exciting new functionalities.

Keywords: EngBio; biofilm engineering; functional biofilms; genetic circuits; optogenetics; synthetic regulation.