[Case of Long-Term Survival after Definitive Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma]

Gan To Kagaku Ryoho. 2024 Nov;51(11):1161-1164.
[Article in Japanese]

Abstract

67-year-old woman underwent definitive chemoradiotherapy( dCRT) with cisplatin( CDDP) and 5-fluorouraci(l 5-FU)(FP) for locally advanced unresectable squamous cell carcinoma of the thoracic esophagus. During treatment, the patient developed grade 3 pharyngitis and esophagitis as adverse events. She was administered maintenance chemotherapy with 2 courses of FP and achieved complete response. Currently, she experiences esophageal stenosis; however, she remains alive and recurrence-free 9 years after initial treatment. While dCRT is effective for locally advanced esophageal cancer, its adverse effects may persist. Herein, we report our case and have included relevant literature considerations.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols* / therapeutic use
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / therapy
  • Chemoradiotherapy*
  • Cisplatin* / administration & dosage
  • Esophageal Neoplasms* / pathology
  • Esophageal Neoplasms* / therapy
  • Esophageal Squamous Cell Carcinoma* / pathology
  • Esophageal Squamous Cell Carcinoma* / therapy
  • Female
  • Fluorouracil / administration & dosage
  • Humans
  • Time Factors

Substances

  • Cisplatin
  • Fluorouracil