Widespread Cutaneous Indeterminate Dendritic Cell Tumor (IDCT) With ETV3::NOAC2 Rearrangement Successfully Treated With PUVA Therapy: A Case Report

Akshay Deshpande; Zbigniew Rudzki; Jaideep Bhat; Matthew Pugh; Susan Rose; Shankara Paneesha

doi:10.1155/crh/8013335

Widespread Cutaneous Indeterminate Dendritic Cell Tumor (IDCT) With ETV3::NOAC2 Rearrangement Successfully Treated With PUVA Therapy: A Case Report

Case Rep Hematol. 2024 Nov 29:2024:8013335. doi: 10.1155/crh/8013335. eCollection 2024.

Authors

Akshay Deshpande¹, Zbigniew Rudzki², Jaideep Bhat³, Matthew Pugh², Susan Rose⁴, Shankara Paneesha^{1

5}

Affiliations

¹ Department of Haematology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
² Department of Histopathology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
³ Department of Dermatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
⁴ West Midlands Regional Genetics Laboratory, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
⁵ Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.

Abstract

The unique histiocytic entity of indeterminate dendritic cell tumor (IDCT) is known to cause diagnostic conundrum and treatment dilemmas with no published consensus on either. We report a rare case of cutaneous IDCT with ETV3::NOAC2 rearrangement providing further evidence to its association with this condition. With its ease of administration and minimal side effects, PUVA therapy can be successfully used to treat cutaneous forms of IDCT.

Publication types

Case Reports