Frequency of Central Serous Chorioretinopathy in a Tertiary Care Center in Pakistan

Background: Central serous chorioretinopathy (CSC) is a significant cause of vision loss in men aged 20 to 60, characterized by serous detachment of the neurosensory retina from the retinal pigment epithelium (RPE). This study aims to assess the frequency of CSC among patients at a tertiary care center in Pakistan, offering insights into its epidemiology and management within this setting.

Methodology: A retrospective observational study was conducted at the ophthalmology department of a tertiary care center from January 2019 to December 2023. Patients aged 20 years and above diagnosed with CSC based on clinical examination, fluorescein angiography (FA), and optical coherence tomography (OCT) were included. Data were collected from electronic medical records, encompassing demographic, clinical, and treatment information. Statistical analysis was performed using IBM SPSS Statistics for Windows, version 25 (IBM Corp., Armonk, NY, USA) with descriptive statistics summarizing demographic and clinical characteristics, and chi-square tests and t-tests examining associations between variables.

Results: A total of 83 patients (112 eyes) were studied, with 83.13% being male and 16.87% female. Unilateral CSC was observed in 65.06% of cases, while 34.94% had bilateral involvement. The age group 25-40 years had the highest incidence (57.83%), with Unani medication (39.58%) and systemic hypertension (45.71%) being the most common contributing factors. The most frequent presenting symptom was vision impairment (48.19%).

Conclusion: CSC primarily affects middle-aged men, with observed associations to factors such as traditional Unani medication and systemic hypertension. This study highlights the importance of tailored treatment strategies and the need for further research into CSC's pathogenesis and management in Pakistan.