Objective Founded in 1873, the Institut universitaire en santé mentale de Montréal (IUSMM) has a captivating history that significantly reflects the evolution of psychiatry over the years. In recent years, the primary sectors of modern medicine have turned to digital health innovations to enhance patient care development. The main objective of this review is to document advancements in digital health within the IUSMM and its affiliated research center over the past 150 years. Method An integrative review focusing on digital health innovations at the IUSMM was conducted. The Medline, Web of Science, PsycNet (PsycINFO), and Google Scholar databases were consulted from their inception until December 2023. Result The literature review initially identified 239 articles, with 108 duplicates removed during the preliminary analysis. Among the remaining 131 studies, 63 articles were excluded based on title and abstract review, as they did not meet inclusion criteria. After a comprehensive analysis of the initially selected 68 articles for eligibility evaluation, a total of 22 articles were retained. Five categories of articles were identified: virtual reality, digital applications, remote services and therapies, the use of artificial intelligence, and digital personal assistants. Conclusion On the occasion of the 150th anniversary of the IUSMM, this integrative review reveals that digital health innovations are primarily concentrated in the last decade, suggesting promising potential for digital applications in supporting individuals with mental health disorders, although the transition to clinical practice may progress slowly.