SIOOT recommendations for the optimal application of the oxygen-ozone therapy in clinical medicine

Int Immunopharmacol. 2025 Jan 3:145:113751. doi: 10.1016/j.intimp.2024.113751. Epub 2024 Dec 9.

Abstract

Oxygen-ozone therapy has garnered increasing attention for its potential therapeutic applications, yet its widespread adoption is hindered by inconsistent protocols and a lack of standardized guidelines. Standardizing these protocols is essential to ensure the safety, efficacy, and reproducibility of treatments. Advanced training for physicians and caregivers is paramount, equipping them with evidence-based knowledge and practical expertise to administer this therapy effectively while avoiding unverified or misleading innovative approaches. Scientific Societies play a pivotal role in this endeavour, providing a structured framework for research, education, and dissemination of validated practices, thereby safeguarding patient welfare and fostering the responsible evolution of the field.

MeSH terms

  • Humans
  • Oxygen* / therapeutic use
  • Ozone* / therapeutic use

Substances

  • Oxygen
  • Ozone