In an era so focused on sustainability, it is important to improve chemical processes by developing and using more environmentally friendly solvents and technologies. Deep eutectic solvents (DES) have proven to be a promising replacement for conventional solvents. In recent years, a new type of DES has emerged that responds to various stimuli. These responsive DES (RDES) may offer all the advantages of DES while allowing the recycling and reuse of solvents. As such, RDES can further contribute to a greener future. This review provides an overview of the diverse types of RDES, their switching mechanisms and their application in several fields. Lastly, it offers a critical perspective on current shortcomings and prospects.