Percutaneous microwave ablation for aldosterone-producing adenoma

Thirty-five patients diagnosed with aldosterone-producing adenomas underwent CT-guided percutaneous microwave ablation (MWA). Comparisons of aldosterone-to-renin ratio (ARR), potassium level, blood pressure (BP), and medications were performed preoperatively, postoperatively, and at the latest follow-up examination. The outcome assessment was based on the primary aldosteronism surgical outcome (PASO) Standards. Hypokalemia was corrected in all patients. The BP postoperatively and at the latest follow-up (138 [128-152]/85 [75-95], 130 [120-140] /85 [80-90]) were significantly lower than preoperative BP (156 [149-170]/ 100 [90-106]). The number of antihypertensive medications was reduced from three (2-3) to one (0-1). The biochemical outcomes were as follows: complete success (CS), 89%; partial success (PS), 7%; and absent success (AS), 4%. The clinical outcomes were as follows: CS 37 %, PS 60%, AS 3%. CT-guided percutaneous MWA is an effective treatment for APA with biochemical and clinical outcomes comparable to adrenalectomy in the PASO standard.