Characteristic Imaging Feature of Cortical Dysgenesis in Tubulinopathy

Bheru Dan Charan; Shailesh B Gaikwad; Tanya Dixit

doi:10.1016/j.wneu.2024.12.019

Characteristic Imaging Feature of Cortical Dysgenesis in Tubulinopathy

World Neurosurg. 2024 Dec 27:193:306-307. doi: 10.1016/j.wneu.2024.12.019. Online ahead of print.

Authors

Bheru Dan Charan¹, Shailesh B Gaikwad², Tanya Dixit³

Affiliations

¹ Radio diagnosis, All India Institute of Medical Sciences, Rishikesh, India.
² Neuroimaging and Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India.
³ Neuroimaging and Interventional Neuroradiology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: [email protected].

PMID: 39662624
DOI: 10.1016/j.wneu.2024.12.019

Abstract

Tubulin-related cortical dysgenesis or tubulinopathies include a wide range of brain cortical malformations that result from defects in genes responsible for the tubulin protein. Tubulin is an integral part of the cell cytoskeleton, and the development of the central nervous system depends on it. We present a case with characteristic imaging features that suggested tubulinopathy.

Keywords: Cortical malformation; Tubulin.