A woman in her 60s with cirrhosis and hepatitis C virus with sustained virologic response underwent multiple local treatments for hepatocellular carcinoma (HCC) starting in April 20xx. Computed tomography in December 20xx+6 revealed HCC recurrence and mass in left kidney. Pathologic evaluation after partial nephrectomy led to the diagnosis of renal metastasis of HCC, and treatment with atezolizumab and bevacizumab was initiated. Complete response was observed with imaging after 13 cycles;however, computed tomography after 19 cycles revealed multiple metastatic lesions in left perirenal space. Multidisciplinary treatment implemented thereafter has led to disease control for about 18 months.