The Novel HLA-C*03:656 Allele Identified by Next-Generation Sequencing

HLA. 2024 Dec;104(6):e15801. doi: 10.1111/tan.15801.

Abstract

HLA-C*03:656 differs from HLA-C*03:04:01:02 by a single missense nucleotide substitution in codon 342 in exon 7.

Keywords: HLA; NGS; novel allele.

Publication types

  • Letter

MeSH terms

  • Alleles*
  • Amino Acid Substitution
  • Base Sequence
  • Codon
  • Exons*
  • HLA-C Antigens* / genetics
  • High-Throughput Nucleotide Sequencing* / methods
  • Histocompatibility Testing* / methods
  • Humans
  • Mutation, Missense
  • Sequence Alignment
  • Sequence Analysis, DNA / methods

Substances

  • HLA-C Antigens
  • Codon
  • HLA-C*03 antigen