A neuronal gene that loops the loop

Science. 2024 Dec 13;386(6727):1223-1224. doi: 10.1126/science.adu0431. Epub 2024 Dec 12.

Abstract

Noncoding RNA controls the expression of a gene implicated in drug- and stress-induced behaviors.

Publication types

  • News
  • Comment

MeSH terms

  • Adaptation, Psychological* / drug effects
  • Adaptation, Psychological* / physiology
  • Animals
  • Basic Helix-Loop-Helix Transcription Factors* / genetics
  • Cocaine* / pharmacology
  • Emotions* / drug effects
  • Emotions* / physiology
  • Enhancer Elements, Genetic*
  • Female
  • Gene Expression Regulation*
  • Humans
  • Male
  • Mice
  • Neurons* / drug effects
  • Neurons* / metabolism
  • R-Loop Structures*
  • RNA, Untranslated* / genetics

Substances

  • RNA, Untranslated
  • Cocaine
  • Npas4 protein, mouse
  • Basic Helix-Loop-Helix Transcription Factors