Young adults with HIV (YAHIV) may be particularly vulnerable to the impact of the COVID-19 pandemic. In this context, associated mitigation measures among YAHIV can adversely impact fragile social and economic systems. We examined the impact of the pandemic and related government-mandated restrictions among YAHIV in Kisumu, Kenya. Between April-May 2021, a cross-sectional survey was conducted among a convenience sample of YAHIV 18-25 years receiving HIV care in Kisumu, Kenya. The information collected included demographics, COVID-19 knowledge, protective measures, and the impact of the pandemic and related restrictions on their daily lives and well-being since the start of the pandemic (i.e., curfews, lockdowns, school/workplace closures). Responses were analyzed using descriptive statistics. Of 275 YAHIV: median age 22 years (IQR: 19-24 years); 178 (65%) female; 222 (81%) completed some secondary education or higher; 108 (39%) lived in an informal housing area. Awareness of COVID-19 was high (99%), mean knowledge score was 4.32 (SD: 0.93; range 1-5) and most reported taking protective measures. Overall, 193 (70%) reported they were affected by COVID-19 and associated restrictions. Almost half (49%) reported changes in a living situation; 24% living with different people, 11% had moved/relocated, and 5% were newly living on the street. Additionally, respondents reported increased verbal arguments (30%) and physical conflict (16%) at home with 8% reporting someone having used/threatened them with a weapon, 12% experiencing physical abuse, 7% being touched in a sexual way without permission, and 5% had forced sex. Impacts of the pandemic and related restrictions were felt across various aspects of YAHIV's lives, including disrupted living situations and increased exposure to verbal and physical conflict, including sexual violence. Interventions are needed to address the impact and potential negative long-term effects of the pandemic on YAHIV health and well-being.
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