Probiotics as an adjunctive therapy in periodontitis treatment-reality or illusion-a clinical perspective

NPJ Biofilms Microbiomes. 2024 Dec 16;10(1):148. doi: 10.1038/s41522-024-00614-5.

Abstract

Periodontitis, a prevalent oral health issue, involves various microorganisms and clinical effects. This review examines probiotics as adjunctive therapy for periodontitis by analyzing forty clinical studies. Findings showed mixed results due to differences in study design, probiotic types, and clinical parameters; however, probiotics improved outcomes in severe cases. Caution is advised when interpreting these results, as longer follow-up periods reveal variability and potential regression in effects.

Publication types

  • Review

MeSH terms

  • Humans
  • Periodontitis* / microbiology
  • Periodontitis* / therapy
  • Probiotics* / administration & dosage
  • Probiotics* / therapeutic use
  • Treatment Outcome