[Therapeutic efficacy of ear endoscopic surgery for middle ear cholesterol granuloma]

Zhonghua Yi Xue Za Zhi. 2024 Dec 24;104(48):4417-4421. doi: 10.3760/cma.j.cn112137-20240629-01458.
[Article in Chinese]

Abstract

This study aimed to investigate the surgical efficacy of middle ear cholesterol granuloma using otoendoscopy. A total of 23 patients (9 males and 14 females) aged (38±18) years who were diagnosed with middle ear cholesterol granuloma at the Otology Medical Center, the First People's Hospital of Foshan from May 2020 to August 2023 were retrospectively analyzed. Based on clinical characteristics of the lesions, the patients were categorized into retention type and granulation type; the latter was further subdivided into localized and extensive types. Endoscopic intervention was performed on four patients with retention-type lesions. Nineteen cases presented as granulation type, among which eleven were classified as localized type and successfully treated via endoscopy. Among eight patients with extensive-type lesions, five adult patients underwent open endoscopic surgery for tympanic sinus and mastoid process reconstruction, and three children received endoscopic surgery along with microscopic closure techniques. During follow-up for at least one year, post-extubation fluid accumulation occurred in one patient, and no recurrence was observed in others. The current study suggests that endoscopic treatment for middle ear cholesterol granuloma yields favorable outcomes.

本研究探讨了耳内镜下中耳胆固醇肉芽肿手术的治疗效果。回顾性纳入佛山市第一人民医院耳医学中心2020年5月至2023年8月收治的确诊为中耳胆固醇肉芽肿的患者23例,男9例,女14例,年龄(38±18)岁,根据病变临床特点分为潴留型和肉芽型,后者又分为局限型和广泛型。4例潴留型患者给予耳内镜下鼓膜置管。19例为肉芽型,其中11例为局限型,给予耳内镜下精准定位切除病变。8例为广泛型,其中5例成人患者给予耳内镜下开放式手术,充填鼓窦及乳突;3例为儿童患者,给予耳内镜联合显微镜闭合式手术。所有患者术后至少随访1年,仅1例拔管后再积液,其余患者术后均未见复发。研究结果提示耳内镜下处理中耳胆固醇肉芽肿效果良好。.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Cholesterol*
  • Ear, Middle* / surgery
  • Endoscopy*
  • Female
  • Granuloma* / surgery
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Cholesterol