Small RNA sequencing data of plasma extracellular vesicles in a breast cancer screening population

Sci Data. 2024 Dec 18;11(1):1381. doi: 10.1038/s41597-024-04164-5.

Abstract

The pathogenesis of breast cancer is still unclear. Small RNAs associated with extracellular vesicles (EVs) have been found to be involved in tumor development. It is important to explore the role of EVs small RNAs in breast cancer. In this study, we established a plasma EVS-associated small RNA dataset that included 120 women who were positive for breast cancer screening and 60 women who were negative. These small RNA included 2656 miRNAs, 728 piRNAs, and 154 tsRNAs. These data provide a reference for researchers to explore molecular diagnostic biomarkers for early breast lesions.

Publication types

  • Dataset

MeSH terms

  • Biomarkers, Tumor / blood
  • Biomarkers, Tumor / genetics
  • Breast Neoplasms* / blood
  • Breast Neoplasms* / genetics
  • Early Detection of Cancer*
  • Extracellular Vesicles* / genetics
  • Extracellular Vesicles* / metabolism
  • Female
  • Humans
  • MicroRNAs* / blood
  • MicroRNAs* / genetics
  • Sequence Analysis, RNA

Substances

  • MicroRNAs
  • Biomarkers, Tumor