Pulmonary thromboembolism due to Mycoplasma pneumoniae in children: a case report and literature review

BMC Pediatr. 2024 Dec 19;24(1):816. doi: 10.1186/s12887-024-05283-z.

Abstract

Background: Mycoplasma pneumoniae (MP) is a common respiratory pathogen in children that can sometimes lead to extrapulmonary manifestations. Among these, pediatric pulmonary thromboembolism (PE) is clinically rare but carries significant implications. However, it is often underrecognized, and its diagnosis and treatment are not well understood.

Case presentation: We report a case of PE associated with MP pneumonia in a 6-year-old girl who presented with recurrent hyperpyrexia, cough, extensive consolidation in the upper lobe of the left lung, and pulmonary artery thrombi in the right lung. Following prompt diagnosis of PE and appropriate antibiotic therapy combined with anticoagulation treatment, the child recovered well and remained healthy at follow-up. The diagnostic and treatment processes were analyzed, and previously reported cases of pediatric MP-related PE were reviewed.

Conclusion: PE should be considered in pediatric patients with MP pneumonia who do not improve or whose condition worsens despite standard therapy. The outcomes of pediatric MP-related PE are generally favorable if prompt diagnosis and appropriate treatment are provided.

Keywords: Case report; Children; Mycoplasma pneumoniae; Pneumonia; Pulmonary thromboembolism.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-Bacterial Agents* / therapeutic use
  • Anticoagulants / therapeutic use
  • Child
  • Female
  • Humans
  • Mycoplasma pneumoniae* / isolation & purification
  • Pneumonia, Mycoplasma* / complications
  • Pneumonia, Mycoplasma* / diagnosis
  • Pneumonia, Mycoplasma* / drug therapy
  • Pulmonary Embolism* / diagnosis
  • Pulmonary Embolism* / etiology
  • Pulmonary Embolism* / microbiology

Substances

  • Anti-Bacterial Agents
  • Anticoagulants