Giant Cystic Pneumocytoma in a Young Male: Rare Diagnostic Conundrum with Clinicoradiological and Histopathological Features

Indian J Radiol Imaging. 2024 Aug 26;35(1):192-195. doi: 10.1055/s-0044-1789244. eCollection 2025 Jan.

Abstract

Pulmonary sclerosing pneumocytoma is a rare benign neoplasm typically seen in middle-aged women. The exact preoperative diagnosis is quite challenging considering its nonspecific clinical and radiologic features along with complex histology. Moreover, obtaining an exact histopathological diagnosis can be difficult especially with the small biopsy specimens. Most patients are generally asymptomatic with incidental detection of peripheral, homogenous, solitary pulmonary nodule. It is essential to differentiate it from other mimickers including malignant lesions as limited surgical resection is curative in these cases without adjuvant therapy. We present a rare giant cystic variant of pneumocytoma, in a young male, which was initially mimicking inflammatory myofibroblastic tumor even on preoperative histology.

Keywords: giant cystic pneumocytoma; inflammatory myofibroblastic tumor; lobectomy; pulmonary sclerosing hemangioma; “air gap sign”; “welt vessel” sign.

Publication types

  • Case Reports

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Funding None.