[Historical evolution and modern research on co-production and processing method of "solid-liquid excipients"]

Zhongguo Zhong Yao Za Zhi. 2024 Nov;49(22):6066-6072. doi: 10.19540/j.cnki.cjcmm.20240723.302.
[Article in Chinese]

Abstract

"Solid-liquid excipients" co-production is one of the typical processing methods of excipients used from ancient times to the present day, and is widely applied in various processing schools and regional specialty varieties. This method significantly reduces the toxicity of traditional Chinese medicine(TCM), moderates medicinal properties, and enhances clinical efficacy. However, modern scientific research has given it limited attention, and many co-production methods of "solid-liquid excipients" have not been applied in production and practice. This paper reviewed the historical development of "solid-liquid excipients" co-production, outlined modern processing standards and methods in different processing schools, and further elaborated on the purposes and effects of this co-production method. This study is expected to provide references and evidence for further in-depth research, inheritance, innovation, and practical application.

Keywords: characteristic processing; processing effects; processing excipient; processing of traditional Chinese medicine.

Publication types

  • Historical Article
  • Review
  • English Abstract

MeSH terms

  • Chemistry, Pharmaceutical* / history
  • Chemistry, Pharmaceutical* / methods
  • Drug Compounding / history
  • Drug Compounding / methods
  • Drugs, Chinese Herbal* / chemistry
  • Excipients* / chemistry
  • History, 20th Century
  • History, 21st Century
  • History, Ancient
  • Medicine, Chinese Traditional / history

Substances

  • Drugs, Chinese Herbal
  • Excipients