[Application and outlook of new technologies and equipment in modern manufacturing of traditional Chinese medicine pills]

Zhongguo Zhong Yao Za Zhi. 2024 Oct;49(19):5125-5134. doi: 10.19540/j.cnki.cjcmm.20240705.601.
[Article in Chinese]

Abstract

Since ancient times, traditional Chinese medicine pills have occupied a key position among different dosage forms of traditional Chinese medicine. With the aims of comprehensively improving the overall quality and innovating key technologies in the manufacturing of the pills, this article elaborates on the principles and new technology applications in pulverizing, sterilization, agglomeration, forming, and drying. In addition, modern technologies such as biosensing, image analysis, texture property evaluation, and moisture analysis can comprehensively and accurately characterize the quality of key materials in the manufacturing of traditional Chinese medicine pills, thereby achieving strict control over the quality of raw materials, intermediates, and final products and further monitoring and optimizing the entire production process of pill preparations. To further improve the production quality and efficiency of traditional Chinese medicine pills, this article briefs the key technologies and equipment schemes for the linkage manufacturing mode and looks forward to the application of the multi-unit linkage manufacturing mode for traditional Chinese medicine pills. This review is expected to provide reference for the research on the multi-unit linkage manufacturing of traditional Chinese medicine pills.

Keywords: key process units; multi-unit linkage manufacturing; new technologies for rapid quality evaluation; quality improvement; traditional Chinese medicine pills.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Drug Compounding / instrumentation
  • Drug Compounding / methods
  • Drugs, Chinese Herbal* / chemistry
  • Humans
  • Medicine, Chinese Traditional*
  • Quality Control
  • Technology, Pharmaceutical

Substances

  • Drugs, Chinese Herbal