[Research progress on "homologous different effects" of Aurantii Fructus Immaturus and Aurantii Fructus]

Aurantii Fructus Immaturus and Aurantii Fructus are the dried young and immature fruits of Rutaceae, which mainly originate from the same part of lime. They are harvested from the same part with different maturity levels, which leads to different medicinal materials. It has been reported that Aurantii Fructus Immaturus and Aurantii Fructus contain flavonoids, alkaloids, volatile oils, coumarins and other components, which have a variety of pharmacological effects such as gastrointestinal disorder-alleviating, anti-anxiety, lipid metabolism-modulating, anti-inflammatory, antimicrobial, and antioxidant effects. This paper reviews the research progress in the evolution, chemical constituents, pharmacological effects, and quality control of Aurantii Fructus Immaturus and Aurantii Fructus, aiming to provide a basis for the quality control and diversified application of the two herbal medicines.