Environmental predictors of SARS-CoV-2 infection incidence in Catalonia (northwestern Mediterranean)

Front Public Health. 2024 Dec 5:12:1430902. doi: 10.3389/fpubh.2024.1430902. eCollection 2024.

Abstract

Numerous studies have explored whether and how the spread of the SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), responds to environmental conditions without reaching consistent answers. Sociodemographic factors, such as variable population density and mobility, as well as the lack of effective epidemiological monitoring, make it difficult to establish robust correlations. Here we carry out a regional cross-correlation study between nine atmospheric variables and an infection index (Ic ) estimated from standardized positive polymerase chain reaction (PCR) test cases. The correlations and associated time-lags are used to build a linear multiple-regression model between weather conditions and the Ic index. Our results show that surface pressure and relative humidity can largely predict COVID-19 outbreaks during periods of relatively minor mobility and meeting restrictions. The occurrence of low-pressure systems, associated with the autumn onset, leads to weather and behavioral changes that intensify the virus transmission. These findings suggest that surface pressure and relative humidity are key environmental factors that may be used to forecast the spread of SARS-CoV-2.

Keywords: COVID-19; atmospheric variables; climate change; environmental sciences; epidemiology; virus spread; weather-infection correlation.

MeSH terms

  • COVID-19* / epidemiology
  • COVID-19* / transmission
  • Humans
  • Humidity*
  • Incidence
  • SARS-CoV-2*
  • Spain / epidemiology
  • Weather*

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This work has been financially supported by the project CLIMATE –COVID19 (Ref. 202030E222) funded by the Spanish National Research Council (CSIC). The work of MM-R has been further supported by Ramón y Cajal (RYC2022-038454-I, funded by MCIN/AEI/10.13039/501100011033 and co-funded by the FSE+, European Union), the DISTROPIA (PID2021-125806NB-I00) and OFF (TED2021-130106B-I00) projects funded by the Spanish Ministry of Science and Innovation. The work of AOA has been supported by the FPU program, funded by the Spanish government (Ministerio de Educacion, Cultura y Deporte, reference FPU17/03796). The authors also recognize the institutional support of the Spanish Government through the Severo Ochoa Center of Excellence accreditation (CEX2019-000928-S).