FAAHcilitating recovery in malnourished kids

Franciscus Chandra; Elaine Y Hsiao

doi:10.1016/j.chembiol.2024.11.007

FAAHcilitating recovery in malnourished kids

Cell Chem Biol. 2024 Dec 19;31(12):2018-2020. doi: 10.1016/j.chembiol.2024.11.007.

Authors

Franciscus Chandra¹, Elaine Y Hsiao²

Affiliations

¹ Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: [email protected].
² Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

PMID: 39706166
DOI: 10.1016/j.chembiol.2024.11.007

Abstract

The molecular underpinnings behind the diet-microbiome-host health relationship are largely undescribed. In a recent issue of Science, Cheng et al.¹ uncovered one piece of the puzzle by describing a novel fatty acid amide hydrolase (FAAH) derived from a Faecalibacterium prausnitzii strain that correlated with improved malnutrition recovery. This emphasized the microbiome's role in supporting recovery from malnutrition.

MeSH terms

Amidohydrolases* / metabolism
Animals
Child
Gastrointestinal Microbiome*
Humans
Malnutrition / metabolism

Substances

Amidohydrolases
fatty-acid amide hydrolase