Pharmacological Block of Genicular Nerves in the Treatment of Knee Osteoarthritis

Rev Bras Ortop (Sao Paulo). 2024 Dec 21;59(6):e888-e894. doi: 10.1055/s-0044-1792117. eCollection 2024 Dec.

Abstract

Objective To evaluate the clinical and functional outcomes of the pharmacological block of the genicular nerves as a modality in the therapeutic arsenal for knee osteoarthritis, since it is simple, safe, and minimally invasive. Methods The pharmacological block of the genicular nerves was performed in 20 patients with grades 3 and 4 knee osteoarthritis per the Kellgren-Lawrence classification. We assessed their clinical and functional outcomes one, three, and six months after the procedure. Results Of the 20 patients undergoing the procedure, 16 (80%) presented an excellent response in the first month of outpatient follow-up, since their pain level went from 8/9 to 2/3; 2 subjects presented a partial response, and 2 others did not respond to the treatment. Conclusion The pharmacological block of the genicular nerves is efficient in reducing pain and improving the performance of daily activities by the patients, especially up to three months after the procedure.

Keywords: nerve block; osteoarthritis, knee; pain.

Grants and funding

Suporte Financeiro Os autores declaram que não receberam suporte financeiros de agências dos setores público, privado ou sem fins lucrativos para a realização deste estudo.