Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male

Urol Case Rep. 2024 Nov 19:58:102884. doi: 10.1016/j.eucr.2024.102884. eCollection 2025 Jan.

Abstract

Sertoli cell tumors are a rare type of sex-cord stromal tumor. We present a case of a thirteen-year-old male presenting with 2-3 months of fevers and twenty-pound weight loss. Evaluation revealed leukocytosis, anemia, elevated systemic inflammatory markers and a negative infectious disease evaluation. An evaluation for malignancy revealed an incidental testicular mass. A radical orchiectomy lead to prompt resolution of fevers, leukocytosis, and elevated systemic inflammatory markers. Final pathology was consistent with a Sertoli cell tumor. To our knowledge, this is the first reported case of a Sertoli cell tumor presenting with fever, leukocytosis, and weight loss.

Keywords: Paraneoplastic syndrome; Pediatric oncology; Sertoli cell tumor; Testicular neoplasms.

Publication types

  • Case Reports