A Rare and Life-Threatening Complication of Salmonella Typhi Infection: A Case Report From India Highlighting Diagnostic and Therapeutic Challenges in Salmonella Sepsis

Salmonella infections are widely known to cause gastroenteritis, especially in areas of poor hygiene and sanitation. Common symptoms include sustained fever, chills, and abdominal pain. Sepsis, disseminated intravascular coagulation (DIC), various neurological manifestations, and multiorgan failure are other uncommon presentations. Raising appropriate awareness about its clinical spectrum is therefore crucial, even in the absence of typical symptoms. The following case of a 34-year-old Indian female who developed Salmonella Typhi-induced sepsis addresses various challenges involved in diagnosing and treating the condition. The case was successfully managed with rapid diagnostics, targeted antibiotic therapy, and supportive care. Recognizing the condition early and providing necessary treatment is therefore vital to preventing substantial morbidity and mortality. To improve outcomes for critically ill patients, it is important that the causative organism be identified quickly and appropriate treatment be commenced. Here, we present a case of Salmonella sepsis complicated by DIC, its clinical course, and the diagnostic and treatment modalities we have followed.