Mushrooms have proven to be a valuable source of diverse bioactive compounds that can hold substantial potential for preventing and managing various diseases. This research focused on examining the numerous bioactive compounds found in Pisolithus albus (P. albus) (Cooke & Massee) Priest mushrooms, particularly those obtained from ethyl acetate and dichloromethane extracts. Polyphenols, flavonoids, tannins, and alkaloids were also evaluated by chemical analysis. Furthermore, the bioactive compounds of extracts were identified using thin-layer chromatography (TLC), gas chromatography-mass spectrometry (GC-MS), and Liquid Chromatography Mass Spectrometry (LC-MS). Evident diversity in the phytochemical composition was noted between the ethyl acetate (EtOAc) and dichloromethane (DCM) extracts, identifying through spectrometric methods interesting bioactive compounds that exhibit potential utility across medicinal and agricultural domains, including their application as herbicides. This study not only shed light on the bioactive constituents within the two types of extracts but also underscored the advantageous compounds inherent in P. albus mushrooms.
Keywords: Pisolithus albus (Cooke & Massee) Priest; Therapeutic compounds; bioactive compounds; secondary metabolites.