Kinetochores get a grip!

J Cell Biol. 2025 Jan 6;224(1):e202411040. doi: 10.1083/jcb.202411040. Epub 2024 Dec 26.

Abstract

A new study by Larson and colleagues (2025. J. Cell Biol.https://doi.org/10.1083/jcb.202405176) reveals that kinetochores are biased to bind to microtubule plus-ends due to an interplay between subcomplex organization and the intrinsic polarity of microtubules.

MeSH terms

  • Animals
  • Humans
  • Kinetochores* / metabolism
  • Microtubules* / metabolism