Comparison of DWI techniques in patients with epidermoid cyst: TGSE-BLADE DWI vs. SS-EPI DWI

Sayo Otani; Yasutaka Fushimi; Sachi Okuchi; Akihiko Sakata; Takayuki Yamamoto; Satoshi Nakajima; Yang Wang; Satoshi Ikeda; Shuichi Ito; Sumika Yasumura; Shigeki Takada; Noritaka Sano; Kentaro Ueno; Yuta Urushibata; Kun Zhou; Yoshiki Arakawa; Yuji Nakamoto

doi:10.1007/s11604-024-01717-x

Comparison of DWI techniques in patients with epidermoid cyst: TGSE-BLADE DWI vs. SS-EPI DWI

Jpn J Radiol. 2024 Dec 28. doi: 10.1007/s11604-024-01717-x. Online ahead of print.

Authors

Sayo Otani¹, Yasutaka Fushimi², Sachi Okuchi¹, Akihiko Sakata¹, Takayuki Yamamoto¹, Satoshi Nakajima¹, Yang Wang¹, Satoshi Ikeda¹, Shuichi Ito¹, Sumika Yasumura¹, Shigeki Takada³, Noritaka Sano³, Kentaro Ueno⁴, Yuta Urushibata⁵, Kun Zhou⁶, Yoshiki Arakawa³, Yuji Nakamoto¹

Affiliations

¹ Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawaharacho, Kyoto, 6068507, Japan.
² Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawaharacho, Kyoto, 6068507, Japan. [email protected].
³ Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
⁴ Department of Biomedical Statistics and Bioinformatics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
⁵ Siemens Healthcare K. K., Tokyo, Japan.
⁶ Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China.

PMID: 39730930
DOI: 10.1007/s11604-024-01717-x

Abstract

Purpose: To compare quantitative values and image quality between single-shot echo-planar imaging (SS-EPI) diffusion-weighted imaging (DWI) and two-dimensional turbo gradient- and spin-echo DWI with non-Cartesian BLADE trajectory (TGSE-BLADE DWI) in patients with epidermoid cyst.

Methods: Patients with epidermoid cyst who underwent both SS-EPI DWI and TGSE-BLADE DWI were included in this study. Two raters placed ROIs encircling the entire epidermoid cyst on SS-EPI DWI, and then on TGSE-BLADE DWI. Apparent diffusion coefficient (ADC) of the epidermoid cyst was measured within each ROI, then the intraclass correlation coefficient (ICC) between raters was obtained for each DWI. The areas of ROIs placed by the two raters were measured and compared using the Dice coefficient. In the selected slice analysis, one rater selected the most appropriate slice and carefully placed the ROIs slightly smaller than the epidermoid outline to avoid artifacts. Image quality analysis was assessed qualitatively for geometric distortion, susceptibility artifacts, lesion conspicuity, and diagnostic confidence. ADCs for both DWI techniques were compared with theoretical values derived from the diffusion phantom.

Results: Twenty patients with epidermoid cyst were included in this study. The ICC of ADC measured by the two raters for TGSE-BLADE (0.80) was higher than that for SS-EPI (0.59). Dice coefficient of ROI areas was significantly higher with TGSE-BLADE (0.78) than with SS-EPI (0.71, P = 0.007). Selected slice analysis showed that the ADC of epidermoid cyst was significantly higher with TGSE-BLADE DWI than with SS-EPI DWI (P < 0.001). ADCs measured from carefully selected ROIs avoiding artifacts with the two techniques correlated positively (r = 0.87, P < 0.001; ICC 0.75). TGSE-BLADE DWI rated better for image quality than SS-EPI DWI according to all raters. ICCs of measured ADC and theoretical ADCs exceeded 0.99 for both techniques.

Conclusions: TGSE-BLADE DWI appears more suitable than SS-EPI DWI for evaluating epidermoid cyst.

Keywords: Diffusion-weighted imaging; Epidermoid cyst; Single-shot echo-planar imaging; TGSE; Turbo gradient- and spin-echo DWI with non-Cartesian BLADE trajectory.

Abstract

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