Ti3C2Tx MXene nanoribbons@MnO2: A novel multifunctional probe for colorimetric and fluorescence dual-response sensing of trichlorfon

Yinhui Yi; Chaofeng Zhang; Yi He; Yue Ren; Libo Li; Tianyan You

doi:10.1016/j.talanta.2024.127473

Ti₃C₂T_x MXene nanoribbons@MnO₂: A novel multifunctional probe for colorimetric and fluorescence dual-response sensing of trichlorfon

Talanta. 2024 Dec 26:286:127473. doi: 10.1016/j.talanta.2024.127473. Online ahead of print.

Authors

Yinhui Yi¹, Chaofeng Zhang², Yi He³, Yue Ren³, Libo Li⁴, Tianyan You⁵

Affiliations

¹ Key Laboratory of Modern Agricultural Equipment and Technology, Ministry of Education, School of Agricultural Engineering, Jiangsu University, Zhenjiang, Jiangsu, 212013, China; School of the Environment and Safety Engineering, And Collaborative Innovation Center of Technology and Material of Water Treatment, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
² School of the Environment and Safety Engineering, And Collaborative Innovation Center of Technology and Material of Water Treatment, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
³ Key Laboratory of Modern Agricultural Equipment and Technology, Ministry of Education, School of Agricultural Engineering, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
⁴ Key Laboratory of Modern Agricultural Equipment and Technology, Ministry of Education, School of Agricultural Engineering, Jiangsu University, Zhenjiang, Jiangsu, 212013, China. Electronic address: [email protected].
⁵ Key Laboratory of Modern Agricultural Equipment and Technology, Ministry of Education, School of Agricultural Engineering, Jiangsu University, Zhenjiang, Jiangsu, 212013, China; College of Agricultural Equipment Engineering, Henan University of Science and Technology, Luoyang, 471003, China. Electronic address: [email protected].

PMID: 39732099
DOI: 10.1016/j.talanta.2024.127473

Abstract

Manganese dioxide nanosheets (MnO₂ NSs) have garnered significant attention in analytical sensing, while the majority of the previous reports suffer from a complex preparation process involving reducing agents, template or high-temperature. In this work, a novel MnO₂ NSs decorated Ti₃C₂T_x MXene nanoribbons (Ti₃C₂T_xNR@MnO₂) composite was firstly assemblied via a facile one-step strategy and applied as a bi-signal generator to enable colorimetric and fluorescence (FL) dual-response sensing. During the assembly process, Ti₃C₂T_xNR innovatively acted as both reductant and carrier to prevent the aggregation of MnO₂ NSs. Benefiting from the strong metal oxide-support interaction (SMOSI) between Ti₃C₂T_xNR and MnO₂, the as-obtained multifunctional probe displayed enhanced oxidase-like activity and oxidation property. The oxidase-like activity and oxidation property of Ti₃C₂T_xNR@MnO₂ were evaluated using 3,3,5,5-tetramethylbenzidine (TMB) and thiamine (TH) as substrates, respectively. In the absence of trichlorfon (TCF), the MnO₂ coating on Ti₃C₂T_xNR surface exhibited specific recognition towards thiocholine (TCh), which originated from the hydrolysis of acetylthiocholine catalyzed by acetylcholinesterase (AChE). Consequently, TCh caused decomposition of MnO₂ into Mn²⁺, resulting in diminished colorimetric and FL signals. However, in the presence of TCF, its inhibitory effect on AChE activity prevented the resolution of MnO₂ into Mn²⁺ by TCh, thereby restoring both colorimetric and FL signals. More importantly, the strong SMOSI effect and TCh-specific recognition unit of Ti₃C₂T_xNR@MnO₂ led to an enhanced detection sensitivity of the dual-mode sensor, which presented a low detection limit of 0.0856 and 0.798 ng mL^-1 using colorimetric and FL measurements, respectively. In summary, this approach presents a new inspiration to construct multifunctional probe for convenient and accurate detection in biosensing.

Keywords: Colorimetric; Fluorescence; Metal oxide-support interaction; Multifunctional Ti(3)C(2)T(x)NR@MnO(2); TCh-specific recognition unit; Trichlorfon.