[Management recommendations of metastatic cervical carcinoma from an unknown primary]

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Dec 7;59(12):1389-1392. doi: 10.3760/cma.j.cn115330-20240721-00434.
[Article in Chinese]

Abstract

原发灶不明颈部淋巴结转移癌是指癌细胞转移至颈部淋巴结而检查不能发现肿瘤原发灶的头颈部癌,病理类型主要是鳞状细胞癌(鳞癌)。基于众多研究表明,以往原发灶不明的颈部转移性鳞癌(cervical metastastic squamous cell carcinoma of unknown primary,CMSCCUP)大多数肿瘤原发灶被证实为人乳头状瘤病毒(HPV)相关口咽癌,以及美国癌症联合委员会第八版头颈癌症TNM分期显示的HPV相关口咽癌、鼻咽癌T0分期的特殊性,我们认为,CMSCCUP可以分为三种类型:HPV相关型、EBV相关型及非HPV/EBV相关型。这样分型,可以使得当前CMSCCUP临床诊断与治疗的思路变得更为清晰。.

MeSH terms

  • Carcinoma, Squamous Cell* / pathology
  • Carcinoma, Squamous Cell* / secondary
  • Carcinoma, Squamous Cell* / therapy
  • Female
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / therapy
  • Humans
  • Lymphatic Metastasis
  • Neoplasm Staging
  • Neoplasms, Unknown Primary* / pathology
  • Neoplasms, Unknown Primary* / therapy