Therapeutic efficacy of immunotherapy for gastric cancer metastasis

World J Gastrointest Surg. 2024 Dec 27;16(12):3881-3886. doi: 10.4240/wjgs.v16.i12.3881.

Abstract

Gastric cancer (GC) metastasis is the main cause of poor prognosis for GC patients. In recent years, breakthroughs in immunotherapy have been made in the treatment of many kinds of cancers, providing new hope for patients with GC metastasis. This paper reviews the mechanism of immunotherapy in GC metastasis and its clinical application, and discusses and compares the research and efficacy of immunotherapy in patients with liver metastasis, lung metastasis, peritoneal metastasis and lymph node metastasis of GC. This study explores the challenges and future development directions of immunotherapy, and provides a theoretical basis and clinical guidance for the precise treatment of patients with GC metastasis.

Keywords: Gastric cancer; Immunotherapy; Liver metastasis; Lung metastasis; Metastasis; Peritoneal metastasis.