Grimontia hollisae Sepsis in a 9-Month-Old Female Infant: A Case Report

Clin Case Rep. 2024 Dec 29;13(1):e70039. doi: 10.1002/ccr3.70039. eCollection 2025 Jan.

Abstract

Grimontia hollisae, an uncommon cause of sepsis, was identified in a 9-month-old infant in Africa without confirmed seafood consumption. Prompt diagnosis through blood culture and targeted antibiotic therapy ensured recovery, emphasizing the need for increased awareness, enhanced diagnostic tools, and active monitoring of emerging pathogens in tropical and resource-limited regions. We present a case report involving a 9-month-old infant who exhibited symptoms of acute gastroenteritis. The blood culture revealed G. hollisae. We treated the infant on empirical first-line antibiotics of IV ceftriaxone, IV gentamicin, zinc tablets, and syrup paracetamol for 5 days after which the child was discharged on oral metronidazole following resolution of symptoms. This case highlights the importance of G. hollisae in causing sepsis in infants in tropical settings. It also emphasizes the need for blood culture investigation and administering the appropriate antibiotics in the diagnosis of children presenting with suspected sepsis.

Keywords: African region; Grimontia hollisae; acute gastroenteritis; case report; sepsis.