The efficacy analysis of laparoscopic-assisted Soave procedure for Hirschsprung's disease in neonates and infants within 3 months of age

Sci Rep. 2024 Dec 30;14(1):31924. doi: 10.1038/s41598-024-83422-3.

Abstract

To evaluate the efficacy of laparoscopic-assisted Soave procedure of Hirschsprung's Disease (HSCR) in neonates and infants within 3 months of age. Patients with HSCR who were admitted to the Department of Fetal and Neonatal Surgery of Hunan Children's Hospital from June 2012 to July 2020 and underwent laparoscopic-assisted Soave procedure were selected. The clinical manifestations, surgical procedures, postoperative fecal contamination, constipation, enterocolitis, and defecation function were analyzed. A total of 267 children were included, 230 males and 37 females. Vaginal delivery occurred in 138 cases (51.7%) and cesarean delivery in 129 cases (48.3%). There were 217 cases (81.3%) of delayed excretion of meconium, preoperative HAEC (Hirschsprung's Disease Associated enterocolitis) 116 cases (43.4%), postoperative HAEC 54 cases (20.2%), 1 cases of postoperative death, 266 cases (99.6%) were cured. There were 37 cases (13.9%) of long-segment type, 226 cases (84.6%) of common type, and 4 cases (1.5%) of short-segment type. Of the 267 cases, 214 cases were followed up (80.1%), 60 cases with fecal contamination, the incidence rate was 28.0%, and 5 cases were tertiary fecal contamination. The overall incidence of constipation was 3.7% (8 cases), and 2 cases were third-degree constipation. Evaluation of defecation function: The excellent rate was 94.4%. Laparoscopic-assisted Soave procedure in neonates and infants within 3 months of age is generally safe and feasible, most infants have good postoperative defecation function, and the incidence of postoperative fecal contamination, constipation, and enterocolitis is relatively low.

Keywords: Constipation; Defecation function; Enterocolitis; Hirschsprung disease.

MeSH terms

  • Constipation / etiology
  • Constipation / surgery
  • Enterocolitis / epidemiology
  • Enterocolitis / etiology
  • Female
  • Hirschsprung Disease* / surgery
  • Humans
  • Infant
  • Infant, Newborn
  • Laparoscopy* / adverse effects
  • Laparoscopy* / methods
  • Male
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Treatment Outcome