Primary uterine non-Hodgkin's lymphoma:a rare case report and review of the literature

Front Oncol. 2024 Dec 18:14:1462353. doi: 10.3389/fonc.2024.1462353. eCollection 2024.

Abstract

Primary uterine non-Hodgkin lymphoma (NHL) is rarely reported, as its incidence is extremely low. We describe a 72 year old patient with primary uterine non-Hodgkin's lymphoma stage IV, diffuse B-cell large cells, who responded well to cytotoxic chemotherapy (R-CHOP). Radiological investigations exhibited certain characteristics, including magnetic resonance T2 weighted imaging, enhanced scanning, diffusion weighted imaging and apparent diffusion coefficient values. The lesion in the anterior wall of the uterine body was relatively large, with a size of about 34mm×47mm×43mm. The gold standard for diagnosis is still the pathological examination of a biopsy specimen, which revealed diffuse large cell of B lineage. This article reviews data collected from 141 patients in the literature.

Keywords: diffuse large b-cell lymphoma (DLBCL); diffusion weighted imaging; magnetic resonance (MR) imaging; non Hodgkin lymphoma (NHL); primary uterine non-Hodgkin lymphoma (NHL).

Publication types

  • Case Reports

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. We were supported by Natural Science Foundation of Inner Mongolia Autonomous Region of china (No.2024MS08006, No.2020MS08128).