Myocardial mechanical changes before and after bariatric surgery in individuals with obesity and diabetes: a 1-year follow-up study

Sci Rep. 2025 Jan 2;15(1):580. doi: 10.1038/s41598-024-84282-7.

Abstract

Bariatric surgery may have an effect on myocardial mechanics in individuals with obesity and diabetes. In this study, two-dimensional speckle-tracking echocardiography was applied to evaluate the changes of left ventricular myocardial mechanics in individuals with obesity and diabetes before and after bariatric surgery. A total of 58 individuals with obesity were divided into an obesity-only group (30 patients) and an obesity + diabetes group (28 patients). Routine echocardiographic parameters and left ventricular global longitudinal strain (GLS) were compared between the two groups at baseline and 6 and 12 months postoperatively. At all three time points, GLS was lower in the obesity + diabetes group than in the obesity-only group. In both groups, the GLS increased successively at 6 and 12 months postoperatively. The change in GLS (∆GLS) from baseline to 6 months was higher than the △GLS from 6 to 12 months in both groups. The △GLS from baseline to 6 months was lower in the obesity + diabetes group than in the obesity-only group. Therefore, obese individuals can benefit from bariatric surgery, which includes improved heart function, delayed disease progression.

Keywords: Bariatric surgery; Diabetes mellitus; Myocardial mechanics; Obesity; Speckle-tracking echocardiography.

MeSH terms

  • Adult
  • Bariatric Surgery* / methods
  • Diabetes Mellitus / physiopathology
  • Diabetes Mellitus, Type 2 / physiopathology
  • Diabetes Mellitus, Type 2 / surgery
  • Echocardiography*
  • Female
  • Follow-Up Studies
  • Heart Ventricles / diagnostic imaging
  • Heart Ventricles / physiopathology
  • Humans
  • Male
  • Middle Aged
  • Myocardium / metabolism
  • Obesity* / physiopathology
  • Obesity* / surgery
  • Ventricular Function, Left / physiology