Purpose: To report a case of bilateral anterior uveitis, pigmentary retinopathy, and pars plana exudates in a patient with Celiac disease with complete resolution of inflammation following gluten-free diet.
Methods: Retrospective case report.
Results: A 19-year-old Asian Indian girl presented with bilateral non-granulomatous anterior uveitis for the past 2 months. Examination revealed bilateral pigmentary retinopathy and exudates near the inferior pars plana in the left eye. Laboratory evaluation revealed positive anti-tissue transglutaminase antibody, low thyroid stimulating hormone, low serum ferritin, anemia, and vitamin D deficiency. Her duodenal biopsy was confirmatory for Celiac disease. After initiation of gluten-free diet, there was complete resolution of anterior segment inflammation and vitreous exudates.
Conclusions: Celiac disease is a rare cause of corticosteroid-resistant uveitis with a handful of cases reported in the literature. This condition has protean manifestations and resolves with gluten-free diet.