Deep learning in 3D cardiac reconstruction: a systematic review of methodologies and dataset

Med Biol Eng Comput. 2025 Jan 4. doi: 10.1007/s11517-024-03273-y. Online ahead of print.

Abstract

This study presents an advanced methodology for 3D heart reconstruction using a combination of deep learning models and computational techniques, addressing critical challenges in cardiac modeling and segmentation. A multi-dataset approach was employed, including data from the UK Biobank, MICCAI Multi-Modality Whole Heart Segmentation (MM-WHS) challenge, and clinical datasets of congenital heart disease. Preprocessing steps involved segmentation, intensity normalization, and mesh generation, while the reconstruction was performed using a blend of statistical shape modeling (SSM), graph convolutional networks (GCNs), and progressive GANs. The statistical shape models were utilized to capture anatomical variations through principal component analysis (PCA), while GCNs refined the meshes derived from segmented slices. Synthetic data generated by progressive GANs enabled augmentation, particularly useful for congenital heart conditions. Evaluation of the reconstruction accuracy was performed using metrics such as Dice similarity coefficient (DSC), Chamfer distance, and Hausdorff distance, with the proposed framework demonstrating superior anatomical precision and functional relevance compared to traditional methods. This approach highlights the potential for automated, high-resolution 3D heart reconstruction applicable in both clinical and research settings. The results emphasize the critical role of deep learning in enhancing anatomical accuracy, particularly for rare and complex cardiac conditions. This paper is particularly important for researchers wanting to utilize deep learning in cardiac imaging and 3D heart reconstruction, bringing insights into the integration of modern computational methods.

Keywords: 3D heart reconstruction; Cardiac imaging; Cardiac segmentation; Deep learning; GANs; Graph convolutional networks (GCN); Statistical shape modeling (SSM).

Publication types

  • Review