Breaking the link: IL-6 targeting to uncouple toxicity and efficacy in patients treated with immune checkpoint blockade

Affiliations

• ¹ Drug Development Department (DITEP), Gustave Roussy, Villejuif. Electronic address: [email protected].
• ² AP-HP, GHU Paris Saclay, Internal Medicine Department, Hospital of Bicêtre, Le Kremlin-Bicêtre; Paris Saclay University, INSERM, CEA, Unit U1184, Le Kremlin Bicêtre; Faculty of Medicine, Paris Saclay University, Le Kremlin Bicêtre.
• ³ Faculty of Medicine, Paris Saclay University, Le Kremlin Bicêtre; Rheumatology Department, Assistance Publique-Hôpitaux de Paris (APHP), FHU CARE, Le Kremlin Bicêtre; Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1184, Hôpital Bicêtre, Le Kremlin Bicêtre.
• ⁴ Drug Development Department (DITEP), Gustave Roussy, Villejuif; Faculty of Medicine, Paris Saclay University, Le Kremlin Bicêtre; Institut National de La Santé Et de La Recherche Médicale (INSERM), U1015 & CIC1428, Laboratoire de Recherche Translationnelle en Immunothérapie (LRTI), Villejuif, France.