Pseudomonas aeruginosa Meningitis: A Case Report and Therapeutic Approach

We report the case of a 22-year-old mother with no medical history, admitted for gram-negative meningitis, identified as Pseudomonas aeruginosa, 15 days after spinal anaesthesia. She was initially treated with dual antibiotic therapy, consisting of ceftazidime (2g three times a day) and amikacin. The first lumbar puncture (LP) performed 10 days approximately after the beginning of the treatment found no bacterial growth on the CSF culture. However, after 21 days of well-conducted treatment, she relapsed, and the Pseudomonas aeruginosa was once again detected on the CSF culture. The therapeutic protocol was changed, and she began meropenem and ciprofloxacin, which was pursued for six weeks. She improved clinically and biologically and was discharged after nearly 90 days of hospitalisation.