Adverse childhood experiences and adult alcohol use during pregnancy - 41 U.S. jurisdictions, 2019-2023

Shawn A Thomas; Nicholas P Deputy; Amy Board; Clark H Denny; Angie S Guinn; Kathryn Miele; Janae Dunkley; Shin Y Kim

doi:10.1016/j.ypmed.2025.108219

Adverse childhood experiences and adult alcohol use during pregnancy - 41 U.S. jurisdictions, 2019-2023

Prev Med. 2025 Jan 4:108219. doi: 10.1016/j.ypmed.2025.108219. Online ahead of print.

Authors

Shawn A Thomas¹, Nicholas P Deputy², Amy Board³, Clark H Denny³, Angie S Guinn⁴, Kathryn Miele³, Janae Dunkley⁵, Shin Y Kim³

Affiliations

¹ Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, USA; Epidemic Intelligence Service, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, USA. Electronic address: [email protected].
² Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, USA; US Public Health Service Commissioned Corps, 5600 Fishers Ln, Rockville, MD 20852, USA.
³ Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, USA.
⁴ Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, USA.
⁵ Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, USA; Oak Ridge Institute for Science and Education, 1299 Bethel Valley Rd, Oak Ridge, TN 37830, USA.

PMID: 39761920
DOI: 10.1016/j.ypmed.2025.108219

Abstract

Introduction: Adverse childhood experiences (ACEs) are preventable, potentially traumatic events that occur in childhood. Alcohol use during pregnancy can result in miscarriage, stillbirth, preterm birth, and a range of lifelong behavioral, intellectual, and physical disabilities in the child. Limited research has examined the relationship between ACEs and alcohol use in pregnancy; available studies might not reflect current trends in this relationship.

Methods: Using 2019-2023 Behavioral Risk Factor Surveillance System data from 41 U.S. jurisdictions, the prevalence of self-reported current alcohol use among pregnant persons aged 18-49 years (N = 2371) was estimated by ACEs and selected characteristics. We calculated unadjusted and adjusted prevalence ratios (aPR) for the relationship between ACEs and alcohol use during pregnancy.

Results: The prevalence of current alcohol use was 16.2 % (95 % CI = 11.5-20.9) among pregnant persons who reported experiencing four or more ACEs, and 8.6 % (95 % CI = 5.7-11.5) among those who reported no ACEs. When adjusting for sociodemographic characteristics, pregnant persons who reported four or more ACEs were more likely to report current alcohol use compared to those who reported no ACEs (aPR = 1.8, 95 % CI = 1.1-2.9). Individually, pregnant persons who experienced emotional abuse (aPR = 1.9, 95 % CI = 1.3-2.7) and witnessed intimate partner violence (aPR = 1.6, 95 % CI = 1.1-2.4) were more likely to use alcohol during pregnancy compared to pregnant persons who did not report experiencing these ACEs.

Conclusions: Higher ACE exposure was associated with alcohol use during pregnancy. Steps can be taken to mitigate their potential harms. Clinical and community-level interventions can address ACEs, which might reduce alcohol use during pregnancy.

Keywords: Adverse childhood experiences; Alcohol use; Childhood trauma; Pregnancy.