Heterogenous Epoxidation of Isobutene Selectively Enabled by MoSe2 in Hexafluoroisopropanol (HFIP)

Molecules. 2024 Dec 11;29(24):5844. doi: 10.3390/molecules29245844.

Abstract

Herein, a high selective epoxidation of isobutene was achieved by heterogeneously dispersed MoSe2 with tert-butyl hydroperoxide (TBHP), which further showed versatile substrate scopes and well-retained activity among recycling tests. A rational mechanism is proposed based on extensive control experiments and electron paramagnetic resonance spectroscopy, surprisingly unveiling the metal-oxo and radical mediated pathways dramatically accelerated by hydrogen bonds of hexafluoroisopropanol (HFIP).

Keywords: MoSe2; hexafluoroisopropanol; hydrogen bonding catalysis; olefin epoxidation.