Clustering-based binary Grey Wolf Optimisation model with 6LDCNNet for prediction of heart disease using patient data

Sci Rep. 2025 Jan 8;15(1):1270. doi: 10.1038/s41598-025-85561-7.

Abstract

In recent years, the healthcare data system has expanded rapidly, allowing for the identification of important health trends and facilitating targeted preventative care. Heart disease remains a leading cause of death in developed countries, often leading to consequential outcomes such as dementia, which can be mitigated through early detection and treatment of cardiovascular issues. Continued research into preventing strokes and heart attacks is crucial. Utilizing the wealth of healthcare data related to cardiac ailments, a two-stage medical data classification and prediction model is proposed in this study. Initially, Binary Grey Wolf Optimization (BGWO) is used to cluster features, with the grouped information then utilized as input for the prediction model. An innovative 6-layered deep convolutional neural network (6LDCNNet) is designed for the classification of cardiac conditions. Hyper-parameter tuning for 6LDCNNet is achieved through an improved optimization method. The resulting model demonstrates promising performance on both the Cleveland dataset, achieving a convergence of 96% for assessing severity, and the echocardiography imaging dataset, with an impressive 98% convergence. This approach has the potential to aid physicians in diagnosing the severity of cardiac diseases, facilitating early interventions that can significantly reduce mortality associated with cardiovascular conditions.

Keywords: Binary Grey wolf optimization; Convolutional neural network; Echocardiogram; Heart disease; Improved sailfish optimization algorithm.

MeSH terms

  • Algorithms
  • Cluster Analysis
  • Echocardiography / methods
  • Heart Diseases* / diagnosis
  • Humans
  • Neural Networks, Computer*