Disparities in traumatic brain injury-related deaths-the United States, 2021

Brain Inj. 2025 Feb 23;39(3):187-198. doi: 10.1080/02699052.2024.2415933. Epub 2025 Jan 9.

Abstract

Objectives: This manuscript describes traumatic brain injury (TBI)-related mortality in the United States during 2021, by geography, sociodemographic characteristics, mechanism of injury, and injury intent.

Method: Multivariable modeling of TBI mortality was performed to assess the simultaneous effect of multiple factors (geographic region, sex, race and ethnicity, and age) included in the model. Authors analyzed multiple-cause-of-death data from the National Vital Statistics System and included records when an International Classification of Diseases, Tenth Revision (ICD-10) underlying cause of death injury code, and a TBI-related ICD-10 diagnosis code were both listed.

Results: During 2021, there were 69,473 TBI-related deaths. Rates were highest among older adults, males, and non-Hispanic American Indian/Alaska Native persons. A large proportion of all TBI-related deaths were attributed to unintentional falls and suicides. Model-based rates of TBI mortality revealed a divergent pattern with increasing rates by age group, while rate ratios simultaneously declined with age among specific racial/ethnic groups when compared with non-Hispanic White persons.

Conclusion: Findings indicate unintentional falls and suicides remain a common cause of fatal TBI and specific groups are disproportionally affected by such injuries. Health care providers can play a role by assessing patients at increased risk for TBI and providing referrals for care and culturally tailored interventions when warranted.

Keywords: ICD-10; Traumatic brain injury; fatal injury; health disparities; surveillance.

MeSH terms

  • Accidental Falls / mortality
  • Accidental Falls / statistics & numerical data
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Injuries, Traumatic* / epidemiology
  • Brain Injuries, Traumatic* / mortality
  • Cause of Death / trends
  • Child
  • Child, Preschool
  • Ethnicity / statistics & numerical data
  • Female
  • Health Status Disparities
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • United States / epidemiology
  • Young Adult