Primary splenic diffuse large B-cell lymphoma presenting with a gastrosplenic fistula: Case report

Radiol Case Rep. 2024 Dec 15;20(3):1359-1362. doi: 10.1016/j.radcr.2024.11.072. eCollection 2025 Mar.

Abstract

Primary splenic diffuse large B-cell lymphoma (PS-DLBCL) is a rare manifestation of malignant lymphoma. Although DLBCL is the most common subtype of non-Hodgkin lymphoma, primary splenic involvement is uncommon. Additionally, a gastrosplenic fistula at initial presentation is even more rare and poses a diagnostic challenge for the radiologist. The clinical and imaging picture can be identical to a splenic abscess with a secondary gastrosplenic fistula formation (GSF), leading to a diagnostic conundrum. Hence, radiologists need to be familiar with this entity for correct diagnosis and appropriate clinical management.

Keywords: Fistulization; Gastrosplenic fistula; Necrotic splenic mass.

Publication types

  • Case Reports