Complete genome sequence of Staphylococcus epidermidis B273 and its epidermicin NI01 biosynthesis plasmid

Microbiol Resour Announc. 2025 Jan 10:e0096124. doi: 10.1128/mra.00961-24. Online ahead of print.

Abstract

The human skin commensal Staphylococcus epidermidis produces diverse, therapeutically relevant bacteriocins. We report the complete whole-genome sequence of the nasal isolate S. epidermidis B273, which contains a plasmid with the biosynthetic gene cluster for epidermicin NI01, a broad-spectrum type II antimicrobial peptide.

Keywords: Staphylococcus; bacteriocins; epidermidis.