Propofol-Induced Fasciculations in a Patient With Obstructive Sleep Apnea: A Case Report

We report a case of a 39-year-old male patient who developed propofol-induced fasciculations during the induction of general anesthesia. The patient had a history of moderate obstructive sleep apnea and was intolerant to continuous positive airway pressure therapy. He subsequently underwent the insertion of a hypoglossal nerve stimulator as a viable surgical intervention. The patient had a drug-induced sleep endoscopy that showed a 100% obstruction at the velum and the oropharynx, mainly in the anteroposterior and lateral directions. The patient experienced a smooth induction and emergence from general anesthesia, except for a brief episode of myoclonus-like movement in the bilateral upper extremities after propofol administration. The patient recovered well and reported an improvement in his sleep quality and daytime symptoms.