Restoring bone healing potential

Elife. 2025 Jan 13:14:e105420. doi: 10.7554/eLife.105420.

Author

Inês Sequeira^{1

2}

Affiliations

¹ Centre for Oral Immunobiology and Regenerative Medicine, Institute of Dentistry, Queen Mary University of London, London, United Kingdom.
² Barts Centre for Squamous Cancer, Queen Mary University of London, London, United Kingdom.

Abstract

A combination of intermittent fasting and administering Wnt3a proteins to a bone injury can rejuvenate bone repair in aged mice.

Keywords: Wnt; aging; bone; bone regeneration; cell biology; intermittent fasting; mouse; osteoprogenitors.

© 2025, Sequeira.

Publication types

Editorial

MeSH terms

Animals
Bone Regeneration
Bone and Bones / physiology
Fracture Healing / physiology
Mice
Wnt3A Protein* / metabolism

Substances

Wnt3A Protein