The Novel HLA-C*01:250 Allele, Identified by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual

HLA. 2025 Jan;105(1):e70019. doi: 10.1111/tan.70019.

Authors

Hua-Yue Yang^{1

2}, Song-Song Gong^{1

2}, Li Ma³, Xiao-Zhuang Hu³, Xiao-Hong Cai^{1

2}

Affiliations

¹ Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Blood Transfusion Department, Ruijin Hospital, Medical School of Shanghai Jiao Tong University, Shanghai, China.
³ Shanghai Tissuebank Biotechnology Co. Ltd, Shanghai, China.

PMID: 39807661
DOI: 10.1111/tan.70019

Abstract

The HLA-C*01:250 allele differs from HLA-C*01:02:01:01 by a single non-synonymous nucleotide change in exon 7.

Keywords: HLA‐C*01:250; novel allele; sequencing‐based typing.

© 2025 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Letter

MeSH terms

Alleles*
Asian People* / genetics
Base Sequence*
Codon
East Asian People
Exons*
HLA-C Antigens* / genetics
Histocompatibility Testing*
Humans
Polymorphism, Single Nucleotide
Sequence Alignment
Sequence Analysis, DNA* / methods

Substances

HLA-C Antigens
Codon